Covid-19 vaccine trial set to begin in UK; scientist says 80% chance of success

The race to develop an effective vaccine against the novel coronavirus gathered pace this week, as clinical trials on humans were approved in Germany and launched in the UK.

Though there are now around 150 development projects worldwide, the German and British plans are among only five clinical trials on humans which have been approved across the globe.

In Britain, volunteers in a trial at the University of Oxford are set to be given on Thursday the first dose of a potential vaccine based on a virus found in chimpanzees.

Meanwhile on Wednesday, German regulatory body PEI green-lighted the country’s first trials on human volunteers for a vaccine developed by German firm Biontech and US giant Pfizer.

The Oxford trial, run by the university’s Jenner Institute, will involve 510 volunteers aged between 18 and 55 in the first phase.

Research director Professor Sarah Gilbert estimated that it has around an 80 percent chance of being successful.

The institute aims to develop a million doses of the vaccine by September, so as to distribute it as quickly as possible after approval.

The Oxford trial is part of a nationwide effort in the UK which since Friday has been spearheaded by a government taskforce.In Germany, meanwhile, the PEI said its approval of the Biontech trial marked a “significant step” in making a vaccine “available as soon as possible”.

In the first phase, it will see “200 healthy volunteers aged between 18 and 55 years” vaccinated with variants of the vaccine, while the second phase could see the inclusion of volunteers who belonged to high-risk groups.

On Wednesday, Biontech CEO Ugur Sahin told a press conference that tests would begin “at the end of April”.

He added that the firm expected to have collected first data by “the end of June or beginning of July”.

Biontech also said that they and Pfizer hoped to gain regulatory approval soon to test the same vaccine candidate in the US.

The PEI meanwhile claimed that “further clinical trials of COVID-19 vaccine candidates will start in Germany in the next few months”.

Last month a newspaper report alleged that the US had attempted to buy exclusive rights to vaccine research being carried out by CureVac, another German firm.

Though CureVac and US officials dismissed it as unfounded, the newspaper report caused outrage in Berlin, and prompted Economy Minister Peter Altmaier to declare that “Germany is not for sale”.

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